Micky van de Ven Double Ends Everton's Run at New Stadium
The Dutch defender became the initial backline player to net two goals in a English top-flight game for Spurs since Jan Vertonghen in March 2013.
Key points
Micky Van de Ven heads into the net two times in first half
Everton's defender has goal disallowed after VAR review
Senegalese midfielder nets final goal in dying moments
This loss is Everton's first at their new ground
The Tottenham defender scored on two occasions as Tottenham extended their unbeaten run in away games in the Premier League and handed Everton their initial loss at Hill Dickinson Stadium.
The Toffees were undefeated in their last five matches at their new ground at the dockside location, having left Goodison Park behind after 133 years at the conclusion of the previous campaign.
But Tottenham's leader the Dutchman pounced twice from corners in the opening 45 minutes to put their impressive record at jeopardy, and they were failed to turn it around before the midfielder - assisted by ex-Everton forward the Brazilian - headed home a final goal to put the game to bed.
The Everton defender thought he had levelled the scores a short while after Van de Ven's first goal, glancing a bullet header past the Spurs keeper from an set-piece.
The Portuguese striker, in the meantime, failed to convert a number of chances, while the Italian goalkeeper made a succession of excellent saves to ensure Tottenham went five away games without defeat in the English top flight.
But the video assistant referee stepped in, advising Craig Pawson to check the score on the screen and the referee decided that Jack Grealish and Iliman Ndiaye were in offside positions and had interfered with the Tottenham goalkeeper.
The win moves the manager's side into third place in the Premier League, a handful of points off north London rivals and table-toppers the Gunners.
The Merseyside club remain in 14th position and are six points ahead of the drop zone.
Tottenham analysis: The defender excels in role at each end of pitch
After a uninspiring midweek performance in the Champions League against Monaco, where they mustered a mere attempts on target, the manager opted for the French striker in attack instead of former Toffees player Richarlison.
The summer signing was failed to make much of an impact before being replaced for Richarlison after 60 minutes on the pitch, but it turns out he proved unnecessary in the final outcome.
Defender Van de Ven transformed into an attacking force to be reckoned with.
Tottenham's opening strike came from a well-worked set-piece play, with the midfielder directing the ball toward the face of goal for an unmarked the defender to head home.
And Ven de Ven - filling in as skipper in Cristian Romero's unavailability - added his next goal in added time as he rose above Jordan Pickford to head home.
The Dutchman was just as impressive in defence, partnering well with his defensive colleague as the pair dealt superbly with the 34 crosses thrown their way by Everton.
Everton analysis: Toffees lacking striker's instinct
Everton's recent stadium had been a happy hunting ground, but it appears the freshness may have worn off slightly and fans flocked to the exits after Sarr's final goal for Spurs.
The end in Everton's winning streak at home won't be a massive concern for the manager, but their striker situation will be.
The forward and Thierno Barry - the Toffees' pair of established centre-forwards - had netted just a single goal combined before Sunday's outing.
And they were failed to add to that miserable record on a damp and dreary evening on in Liverpool.
Beto's performance was summed up when he chose to bicycle-kick a clear chance from close range, despite having room and time to readjust for a simpler shot that would have challenged Vicario.
Barry, as well, failed to influence the game after replacing Beto in the 65th minute.
It was not for a shortage of opportunity. Most of the home side's offensive moves came through the winger and the forward, who tirelessly delivered dangerous crosses into the Tottenham penalty area.
Upcoming fixtures for these two sides?
Everton: The team head to Sunderland in the Premier League on early November at 20:00 GMT.
Spurs: Spurs travel to St James' Park on Wednesday, 29 October for their fourth-round League Cup match against Newcastle.